Chenxu has been awarded the National Institutes of Health Director’s New Innovator Award to fund our project to develop single-cell sequencing tools, known collectively as “multi-omics,” to track age-related changes in gene regulation programs, as well as cell decay, in brain cells from preclinical models.

Our immediate goal is to understand the multiple epigenetic changes that regulate gene expression occur in individual brain cells during aging. To do that, we will develop a set of single-cell sequencing tools that will allow him to model the location and timing of changes in epigenetic factors regulating gene expression that are “written and erased” during this period. The tools will be helpful for many other scientists, particularly those studying cancer.

The Director’s New Innovator Award was created in 2007 and focuses on supporting “early-stage investigators of exceptional creativity who propose highly innovative research projects with the potential to produce a major impact on broad, important areas.” This award supported by the National Institutes of Health - National Institute of General Medical Sciences under Award Number DP2GM154011.

For more information, please read the NIH Press Release, Weill Cornell Newsroom, and NYGC News.

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