Welcome to the Zhu Lab
Our goal is to develop innovative multimodal single-cell genomics tools to study the combined effects of multiple regulatory layers in cell fate specification and maintenance, with an emphasis on understanding the molecular logics in development, aging and diseases.
Our lab is located at the New York Genome Center and Weill Cornell Medicine.
Recent News
Paired-Damage-seq is out at Nature Methods! By parallel profiling DNA damage and gene expression in single cells, Paired-Damage-seq revealed the associations between damage formation and epigenetic changes. The distribution of DNA damage hotspots exhibits cell-type-specific patterns, and this selective genome vulnerability could predict the cell types and molecular programs that contribute to disease risks. Read more.
Read moreJoin us!
We actively recruit graduate students (wet-dry hybrid) and postdoctoral associates (dry lab). We are affiliated with the PBSB and Tri-I CBM graduate programs.
If you are excited about developing single-cell epigenomics technologies, making discoveries about gene regulation in development and diseases, please do not hesitate to contact us.
Read moreThe Zhu Lab is supported by:
- NIH Director's New Innovator Award
- NIH-NHGRI Pathway to Independence Award
- Center for Integrated Cellular Analysis
- New York Genome Center
- Weill Cornell Medicine
